Monoamine oxidase inhibition by monoterpene indole alkaloids and fractions obtained from Brazilian Southern Psychotria species
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منابع مشابه
In vitro antioxidant activity of alkaloids from southern Brazilian Psychotria: a comparative analysis
Background Monoterpene índole alkaloids (MIAs) comprise a class of secondary metabolites of dual biosynthetic origin, characterized by the presence of an indole and a terpene portion. MIAs are widely studied because of their bioactive properties and pharmacological potential. In this study, major MIAs from native species of Psychotria of southern Brazil were used: P. brachyceras, P. umbellata a...
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The genus Psychotria (Rubiaceae) comprises more than 2000 species, mainly found in tropical and subtropical forests. Several studies have been conducted concerning their chemical compositions, showing that this genus is a potential source of alkaloids. At least 70 indole alkaloids have been identified from this genus so far. This review aimed to compile 13C-NMR data of alkaloids isolated from t...
متن کاملAlkaloids as Inhibitors of Monoamine Oxidases and Their Role in the Central Nervous System
Chapter Outline Introduction 123 Therapeutic Potential of Monoamine Oxidase Inhibition in Neurological Disorders 124 Depression 125 Parkinson’s Disease 126 Other Neurodegenerative Diseases 126 Smoke and Alcohol Cessation 127 Alkaloids as Monoamine Oxidase Inhibitors 127 Indole Alkaloids 128 Isoquinoline Alkaloids 134 Piperidine Alkaloids 137 Desoxypeganine 138 Other Alkaloids 139 Conclusion 141...
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Recently many people have shown great interest in traditional indigenous practices and popular medicine, involving the ingestion of natural psychotropic drugs. We received a request to analyze and determine the nature of a dark green liquid with a dark brown plant sediment, which the police had seized at an airport and inside the home of a person belonging to the 'Santo Daime' religious movemen...
متن کاملDe novo production of the plant-derived alkaloid strictosidine in yeast.
The monoterpene indole alkaloids are a large group of plant-derived specialized metabolites, many of which have valuable pharmaceutical or biological activity. There are ∼3,000 monoterpene indole alkaloids produced by thousands of plant species in numerous families. The diverse chemical structures found in this metabolite class originate from strictosidine, which is the last common biosynthetic...
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تاریخ انتشار 2012